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Work package 3

Groups oriented to synthetic organic chemistry use the modern methods of organic synthesis to prepare compounds that are based on natural product screening (WP1) or virtual screening of know chemicals (WP2).

These synthesis products will be tested in various protein kinase binding and activity assays to find the hit molecules. This also provides essential feed-back information for the molecular modellers and synthetic chemists to refine the chemical structure of the found hits.

Groups in WP 3:
University of Helsinki
Faculty of Pharmacy
Division of Pharmacology and Toxicology and
Viikki Drug Discovery Technology Center (DDTC)

Prof. Raimo K. Tuominen (project coordinator)
Prof. Jari Yli-Kauhaluoma

CNRS, UMR 5181
Méthodologies de Synthèse et Molécules Bioactives
Université Claude Bernard - Lyon 1

Prof. Peter Goekjian
Prof. Hélène Parrot-Lopez

Prof. Benoît Joseph
Prof. Olivier Piva
Dr. Philippe Belmont
Université Blaise Pascal - Clermont-Ferrand II
Prof. Michelle Prudhomme

University of Braunschweig
Institute of Pharmaceutical Chemistry
Prof. Conrad Kunick